Description
CLS-138 cells, a remarkable biological discovery derived from the primary spindle cell sarcoma of female NMRI mice. These individual cells were cultivated through a fascinating process involving the induction of tumours in female NMRI mice through a single injection of Benzpyrene. CLS-138 cells are a valuable resource for researchers in biological science. These cells offer a powerful tool to explore and understand the intricate mechanisms underlying spindle cell sarcomas, a malignant tumour originating from connective tissue. By studying CLS-138 cells, scientists gain invaluable insights into the complex nature of these tumours and potential avenues for their treatment. These cells provide an exceptional model for investigating the behaviour and characteristics of spindle cell sarcomas. Researchers can examine these cells molecular and genetic aspects, deciphering the underlying genetic mutations and abnormalities that contribute to tumour formation. Such investigations help unravel the intricate interplay of factors that drive the progression and development of spindle cell sarcomas. Furthermore, CLS-138 cells enable scientists to explore potential therapeutic interventions. By subjecting these cells to various experimental treatments, researchers can evaluate the effectiveness of different drugs, compounds, or therapeutic strategies in inhibiting tumour growth and promoting cell death. Such studies contribute to the development of novel and targeted therapies for spindle cell sarcomas, with the ultimate goal of improving patient outcomes and quality of life. Establishing CLS-138 cells from the primary spindle cell sarcoma of female NMRI mice provides a reproducible and reliable experimental system. Researchers can utilize these cells to investigate a wide range of research questions related to spindle cell sarcomas, including identifying biomarkers, examining cellular signalling pathways, and exploring potential prognostic factors. CLS-138 cells offer an exciting avenue for biological research, allowing scientists to delve into the complexities of spindle cell sarcomas. With their origin in the primary spindle cell sarcoma of female NMRI mice induced by Benzpyrene injection, these cells serve as a crucial tool in deciphering the underlying mechanisms of tumour formation and developing innovative strategies for their treatment. Exploring CLS-138 cells opens doors to new possibilities in the fight against spindle cell sarcomas, ultimately aiming for improved patient outcomes and a deeper understanding of this challenging disease